Glycosyl compounds
Medchemexpress LLC Fluorescein Di-β-D-Glucuronide | 134869-04-8 | HY-D1460 | 96.6% | 684.55 | 5 MG
Fluorescein Di-β-D-Glucuronide is a fluorescent probe used for non-invasive imaging of intestinal bacterial β-glucuronidase activity in nude mice. It reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, facilitating pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.
- Fluorescent probe
- Utilized for non-invasive imaging of intestinal bacterial β-glucuronidase activity
- Reveals in vitro and in vivo activity of intestinal bacterial β-glucuronidase
- Facilitates pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors
- Classified as Fluorescent Dye, Enzyme Labeling, Protease Substrate
- Relevant to Disease Areas: Infection, β-glucuronidase, Bacterial
Medchemexpress LLC Galactose 1-phosphate Potassium salt | 19046-60-7 | 99.0% | 336.32 | 25 MG
Galactose 1-phosphate Potassium salt is an intermediate involved in galactose metabolism and nucleotide sugars. It acts as an inhibitor for several enzymatic activities, including phosphoglucomutase, glucose-6-phosphate phosphatase, glucose-6-phosphate dehydrogenase, glycogen phosphorylase, UDP-glucose pyrophosphorylase, and inositol monophosphatase. It is intended for research use only.
- Intermediate in galactose metabolism and nucleotide sugars.
- Inhibitor of various enzymatic activities (phosphoglucomutase, glucose-6-phosphate phosphatase, glucose-6-phosphate dehydrogenase, glycogen phosphorylase, UDP-glucose pyrophosphorylase, and inositol monophosphatase).
- Available in solid and solution forms.
- High purity (99.0%).
Selleck Chemical LLC Orcinol glucoside S3828-5mg
Orcinol glucoside (OG Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn It shows potent antioxidative and anxiolytic activities without sedative effects
Medchemexpress LLC Phenyl β-D-glucopyranoside | 1464-44-4 | 99.85% | 256.25 | 500 MG
Phenyl β-D-glucopyranoside is a component isolated from Phellodendron amurense, which exhibits anti-inflammatory and anti-tumor activities. It inhibits nitric oxide (NO) production and the expression of iNOS and COX-2. Additionally, it inhibits the nuclear translocation of NF-κB and the expression of pro-inflammatory cytokines and related genes.
- Isolated from Phellodendron amurense.
- Anti-inflammatory activity.
- Anti-tumor activity.
- Inhibits nitric oxide (NO) production.
- Inhibits iNOS and COX-2 expression.
- Inhibits nuclear translocation of NF-κB.
- Inhibits expression of pro-inflammatory cytokines and related genes.
Medchemexpress LLC TGFBR2/TGF-beta RII 2ug
TGF-beta receptor 2 Protein Human (HEK293 Fc) a fragment of transforming growth factor-beta receptor type 2 (T RII) consists of amino acid of Thr23-Asp159 with an Fc tag at the C-terminus
Medchemexpress LLC IL-36 beta/IL-1F8 H 500ug
Recombinant human IL-36 beta (IL-1F8) is a tag-free, lyophilized cytokine (153 amino acids) produced in E. coli and supplied for in vitro research. It engages the IL-36 receptor to activate NF-κB and MAPK signaling and is intended for receptor-binding, signaling, and cytokine-response assays. The material is provided at high purity and formulated for stability with recommended frozen storage for long-term use.
- Tag-free recombinant protein expressed in E. coli.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Lyophilized formulation in PBS for storage stability.
- Activates IL-36R and downstream NF-κB and MAPK signaling.
- Suitable for receptor-binding, signaling, and pathway assays.
- Available in multiple sizes, including a 500 μg option for flexible use.
- Stable when frozen; aliquot and store at -20°C or -80°C for extended storage.
Sigma Aldrich Fine Chemicals Biosciences alpha L Iduronidase human
L-Iduronidase (IDUA) is mapped to human chromosome 4p16.3. The mature IDUA protein is glycosylated and comprises triosephosphate isomerase (TIM) barrel domain -sandwich helix-loop-helix region and an immunoglobin-like domain. L-Iduronidase is classified under glycoside hydrolase (GH) family 39.
Selleck Chemical LLC Cucurbitacin D-E0701-1MG
Cucurbitacin D is an active component in Cucurbita texana disrupts maturation of HSP90 and interactions between Hsp90 and two co-chaperones Cdc37 and p23
Medchemexpress LLC Isrib (trans-isomer) | 1597403-47-8 | 99.49% | 451.34 | 50 MG
ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. It effectively reverses the effects of eIF2α phosphorylation and reduces the viability of cells subjected to PERK-activation by chronic endoplasmic reticulum stress. This trans-isomer is 100-fold more potent than cis-ISRIB, demonstrating stereospecific interaction with its cellular target.
- Potently reverses eIF2α phosphorylation (IC50=5 nM)
- Blocks eIF2α phosphorylation-induced stress granule (SG) formation
- Increases long-term memory in rodents
- Readily crosses the blood-brain barrier
Crescent Chemical Co Inc TREHALOSE ANALYTICAL GRADE
Trehalose analytical grade Size - 100G Storage Conditions - +15 °C TO +30 °C Catalog Number - 36770.03 CAS 6138-23-4
Crescent Chemical Co Inc TREHALOSE ANALYTICAL GRADE
Trehalose analytical grade Size - 25G Storage Conditions - +15 °C TO +30 °C Catalog Number - 36770.02 CAS 6138-23-4
Cayman Chemical Dodecnoyl D-Sucrose 250mg
A nonionic surfactant; active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay at 255 mM; immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to uncoated ovalbumin; dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel; has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions
Medchemexpress LLC Saikosaponin D | 20874-52-6 | 99.8% | 780.98 | 1 ML
Saikosaponin D is a triterpene saponin isolated from Bupleurum. It exhibits anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities. Saikosaponin D inhibits selectin, STAT3, and NF-kB, and activates estrogen receptor-β. It is for research use only.
- Isolated from Bupleurum
- Triterpene saponin
- Inhibits selectin, STAT3 and NF-kB
- Activates estrogen receptor-β
- Anti-inflammatory activity
- Anti-bacterial activity
- Anti-tumor activity
- Anti-allergic activity
Medchemexpress LLC D-α-Tocopherylquinone | 7559-04-8 | 5 MG
D-α-Tocopherylquinone is a quinone isolated from *Phaeodactylum tricornutum* and an oxidation product of α-Tocopherol (vitamin E). It functions as an anticoagulant and antioxidant, actively reducing cellular oxidative damage caused by oxidized lipids. The compound binds to a liver cytosolic protein (molecular mass ~40 kDa) and to glutathione-S-transferase (GST), which aids its transport to metabolism sites or excretion in bile.
- Isolated from *Phaeodactylum tricornutum*
- Oxidation product of α-tocopherol (vitamin E)
- Acts as an anticoagulant
- Acts as an antioxidant
- Reduces cellular oxidative damage from oxidized lipids
- Binds to a liver cytosolic protein
- Binds to glutathione-S-transferase (GST)
- Facilitates transport for metabolism or excretion
- Inhibits GST activity dose-dependently